A study compared the effectiveness of two rabies immunoglobulin (RIG) administration methods in post-exposure prophylaxis for patients with category III rabies exposure in India. It assessed wound-only infiltration versus traditional weight-based dosing after a three-dose rabies vaccination. Both methods resulted in adequate antibody responses, with the wound-only approach reducing the volume of RIG used.
Source: The American journal of tropical medicine and hygiene, https://doi.org/10.4269/ajtmh.26-0343